| Name | Wins | Losses | Win % |
|---|---|---|---|
| Rich Harden | 1165 | 793 | 0.595 |
| Huston Street | 1343 | 922 | 0.593 |
| Bobby Crosby | 1188 | 964 | 0.552 |
| Barry Zito | 1031 | 856 | 0.546 |
| Eric Chavez | 1061 | 960 | 0.525 |
| Mark Ellis | 932 | 937 | 0.499 |
| MARCO! | 994 | 1067 | 0.482 |
| Mark Kotsay | 783 | 903 | 0.464 |
| Justin Duchschererer | 684 | 1168 | 0.369 |
| Mark Mulder | 796 | 1407 | 0.361 |